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Tsutomu Hirano Selected Research

oxidized low density lipoprotein

5/2022Metabolic Properties of Lowdensity Lipoprotein (LDL) Triglycerides in Patients with Type 2 Diabetes, Comparison with Small Dense LDL-Cholesterol.
4/2022Dyslipidemia in diabetic kidney disease classified by proteinuria and renal dysfunction: A cross-sectional study from a regional diabetes cohort.
2/2022Favorable therapeutic efficacy of low-density lipoprotein apheresis for nephrotic syndrome with impaired renal function.
1/2022Small Dense LDL Tied to Diabetic Retinopathy-Similarity to Atherosclerosis.
7/2020A Dipeptidyl Peptidase-4 Inhibitor Inhibits Foam Cell Formation of Macrophages in Type 1 Diabetes via Suppression of CD36 and ACAT-1 Expression.
9/2018Pathophysiology of Diabetic Dyslipidemia.
11/2017Correction to: Dapagliflozin decreases small dense low-density lipoprotein-cholesterol and increases high-density lipoprotein 2-cholesterol in patients with type 2 diabetes: comparison with sitagliptin.
6/2017Effect of ezetimibe add-on therapy over 52 weeks extension analysis of prospective randomized trial (RESEARCH study) in type 2 diabetes subjects.
1/2016[Small-Dense LDL, HDL2, 3].
6/2015Immediate therapeutic efficacy of low-density lipoprotein apheresis for drug-resistant nephrotic syndrome: evidence from the short-term results from the POLARIS Study.
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Tsutomu Hirano Research Topics

Disease

37Type 2 Diabetes Mellitus (MODY)
05/2022 - 01/2002
35Atherosclerosis
01/2022 - 03/2003
24Insulin Resistance
09/2020 - 01/2002
17Coronary Artery Disease (Coronary Atherosclerosis)
03/2022 - 01/2002
17Coronary Disease (Coronary Heart Disease)
01/2012 - 01/2002
13Inflammation (Inflammations)
05/2022 - 06/2002
13Hyperlipidemias (Hyperlipidemia)
06/2015 - 01/2002
13Hypertriglyceridemia
04/2014 - 01/2002
11Dyslipidemias (Dyslipidemia)
04/2022 - 01/2002
10Cardiovascular Diseases (Cardiovascular Disease)
05/2022 - 11/2008
10Hypertension (High Blood Pressure)
07/2020 - 06/2002
10Atherosclerotic Plaque (Atheroma)
05/2020 - 06/2006
10Body Weight (Weight, Body)
02/2020 - 07/2012
7Hyperglycemia
07/2020 - 04/2014
7Hypercholesterolemia
06/2017 - 01/2003
6Obesity
02/2020 - 06/2002
5Metabolic Syndrome (Dysmetabolic Syndrome X)
05/2022 - 12/2006
5Proteinuria
04/2022 - 06/2003
5Type 1 Diabetes Mellitus (Autoimmune Diabetes)
07/2020 - 08/2010
5Carotid Artery Diseases
05/2019 - 02/2007
5Diabetic Nephropathies (Diabetic Nephropathy)
09/2018 - 06/2003
4Chronic Kidney Failure (Chronic Renal Failure)
02/2022 - 04/2007
4Glucose Intolerance
01/2017 - 06/2002
4Diabetes Mellitus
01/2014 - 01/2002
3Nephrotic Syndrome (Syndrome, Nephrotic)
02/2022 - 05/2015
3Diabetic Retinopathy (Retinopathy, Diabetic)
01/2022 - 12/2008
3Hyperplasia
01/2018 - 10/2017
3Fibrosis (Cirrhosis)
08/2016 - 03/2012
3Acute Coronary Syndrome
01/2014 - 11/2006
3Myocardial Infarction
10/2008 - 09/2003
2Hypoglycemia (Reactive Hypoglycemia)
02/2020 - 01/2019
2Heart Failure
01/2020 - 01/2014
2Chronic Renal Insufficiency
01/2016 - 04/2014
2Hypoproteinemia
06/2015 - 04/2014
2Renal Insufficiency (Renal Failure)
04/2014 - 12/2007
2Thyroid Diseases (Thyroid Disease)
01/2012 - 08/2010

Drug/Important Bio-Agent (IBA)

49oxidized low density lipoproteinIBA
05/2022 - 01/2002
28Glucose (Dextrose)FDA LinkGeneric
09/2021 - 01/2002
21Triglycerides (Triacylglycerol)IBA
05/2022 - 01/2002
20ApolipoproteinsIBA
03/2022 - 08/2002
17LDL CholesterolIBA
05/2022 - 08/2002
17LipidsIBA
04/2022 - 07/2003
16Apolipoproteins E (ApoE)IBA
03/2022 - 09/2010
14LDL Lipoproteins (beta Lipoproteins)IBA
03/2022 - 01/2002
14Insulin (Novolin)FDA Link
06/2018 - 01/2002
12Lipoproteins (Lipoprotein)IBA
05/2022 - 01/2002
12HDL CholesterolIBA
03/2022 - 07/2003
12Peptides (Polypeptides)IBA
08/2016 - 10/2005
11CholesterolIBA
05/2022 - 12/2002
8HDL LipoproteinsIBA
03/2022 - 05/2004
8Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
06/2017 - 01/2002
7Biomarkers (Surrogate Marker)IBA
05/2022 - 10/2008
7AdiponectinIBA
01/2018 - 06/2002
6Dipeptidyl-Peptidase IV InhibitorsIBA
09/2021 - 01/2016
6IncretinsIBA
02/2020 - 01/2010
6LiraglutideFDA Link
02/2019 - 04/2014
6Vasoconstrictor AgentsIBA
04/2017 - 10/2005
6urotensin IIIBA
06/2009 - 10/2005
6FructoseIBA
01/2008 - 06/2002
5Pharmaceutical PreparationsIBA
04/2022 - 05/2015
5Glucagon (Glukagon)FDA Link
05/2020 - 01/2013
5Glucagon-Like Peptide 1 (GLP 1)IBA
04/2015 - 01/2010
4Fibric Acids (Fibrates)IBA
05/2022 - 01/2002
43- (4- (4- (3- methyl- 1- phenyl- 1H- pyrazol- 5- yl)piperazin- 1- yl)pyrrolidin- 2- ylcarbonyl)thiazolidineIBA
07/2020 - 09/2015
4dapagliflozinIBA
01/2020 - 01/2015
4Glycated Hemoglobin (Glycosylated Hemoglobin)IBA
01/2019 - 01/2014
4Proteins (Proteins, Gene)FDA Link
10/2016 - 06/2002
4Apolipoproteins B (ApoB)IBA
09/2016 - 08/2002
3Streptozocin (Streptozotocin)FDA Link
07/2020 - 10/2003
3Hemoglobins (Hemoglobin)IBA
03/2020 - 01/2014
3gastric inhibitory polypeptide receptorIBA
02/2020 - 08/2016
3Hypoglycemic Agents (Hypoglycemics)IBA
02/2020 - 07/2003
3Angiotensin IIIBA
08/2016 - 04/2006
3pitavastatin (itavastatin)FDA Link
03/2016 - 06/2007
3Messenger RNA (mRNA)IBA
03/2012 - 05/2003
3C-Reactive ProteinIBA
01/2012 - 06/2002
3Heparin (Liquaemin)FDA LinkGeneric
08/2007 - 04/2004
3VLDL LipoproteinsIBA
05/2007 - 08/2002
3olmesartanIBA
01/2006 - 04/2004
2pigment epithelium-derived factorIBA
03/2021 - 03/2015
2AlbuminsIBA
03/2020 - 07/2003
2Glucagon-Like Peptide-1 Receptor AgonistsIBA
02/2020 - 01/2019
2EnzymesIBA
11/2019 - 04/2007
2ImmunosorbentsIBA
11/2019 - 04/2007
2AdipokinesIBA
01/2019 - 05/2016
2LipopolysaccharidesIBA
01/2018 - 01/2018
2Dipeptidyl-Peptidases and Tripeptidyl-PeptidasesIBA
01/2018 - 01/2013
2CollagenIBA
01/2018 - 10/2016
2Sitagliptin Phosphate (Januvia)FDA Link
11/2017 - 01/2017
2Ezetimibe (Zetia)FDA Link
06/2017 - 03/2012
2Sodium-Glucose Transport ProteinsIBA
01/2017 - 01/2015
2Proprotein Convertase 9IBA
09/2016 - 05/2013
2ChylomicronsIBA
04/2014 - 09/2003
2Cholesterol Esters (Cholesteryl Esters)IBA
04/2014 - 09/2010
2salicylhydroxamic acid (SHAM)IBA
03/2012 - 06/2002

Therapy/Procedure

14Therapeutics
02/2020 - 07/2003
4Renal Dialysis (Hemodialysis)
04/2014 - 06/2003
3Blood Component Removal (Apheresis)
02/2022 - 05/2015
2Aftercare (After-Treatment)
01/2019 - 06/2015
2Percutaneous Coronary Intervention
03/2015 - 08/2007